"Use of automated pupillometry remains a value adjunct to traditional invasive therapies. Neuroscience nurses continue to integrate this technology into serial pupil- lary assessments to decrease subjectivity of examina- tions and allow for trending of values. Evaluation of trended pupillometer data not only yields more robust information about pupillary reactivity but may pro- vide important insights into ICP elevations in the absence of invasive monitoring and warrants additional research."

"A sophisticated integration of these two signals (EEG and ICP) can allow us to... understand and possibly detect and correct pathological neurovascular coupling."

"...multimodality data may be useful in interpretation of Critical Care Continuous EEG... Physiologic data streams should be time synchronized with EEG."

"We recommend adopting a database infrastructure that enables the integration of high-resolution physiologic data (including EEG recordings) with lower resolution data from laboratory and electronic health care systems."